A tough game that can go either way. Both teams will have issues stopping the other. The difference is, Oregon proven to have more ways to beat you than CU has so far. Where CU is strong, Oregon is solid or strong, where CU is weak, Oregon isn't as weak or solid at. What Colorado has is Shedeur Sanders and that matters a lot. That said, Alton McCaskill is going to have to be special for CU to win. Travis was the difference against TCU. CU needs a running game that can force more than 5 in a box. When that happens against man coverage, it will be difficult.
If I was Oregon, I wouldn't bring exotic blitzes against Shedeur unless I want to get destroyed. Nebraska did it once Shedeur was out of the game against Staub but refused to do it to Shedeur and even if they did, he would have killed them for it.
Shedeur is the best in the nation at pre snap and post snap reads. You have to play it Mano e Mano like Colorado State did with their pass rush. Anytime Kamara was out, they couldn't get any pressure on Sanders and got dominated.
I don't see Oregon going from what they do. I see them playing man and getting roasted. Their goal is avoid giving up TDs and forcing FGs. Alton going to have to run 20-25 times in my mind. Also this will keep Dylan fresh for a big play or two.