Guys, please refer back to the OP.
Plane is scheduled to land at 10:45.
Got to figure that it's 45 minutes before he has the rental car and is hitting the road (assuming no checked bags).
So if everything goes well, he's leaving the rental lot at 11:30. More likely, it will be 12:00.
Then, normal traffic would be 40 minutes to get onto campus from there. Between the higher traffic, getting parked on a game day, walking to the stadium, getting through security and taking his seat... let's just say that he doesn't have an extra 15 minutes to enjoy the scenic route.
Like I originally posted, I'd go with E-470, jump on 36W in Broomfield, and turn into campus on Colorado. That is your best bet of making it in without being stressed the whole way. Might even get to have a beer or two at the Garden and see Ralphie run if you're flight's on time and your rental company is efficient.