Not really. Look at schedules. You see some conference openers early with ooc games happening later.
Forget the SEC, too. Most of those teams don't want to leave their region. They're much more interested in playing FIU or LA-Monroe or Troy than they are a team from Kansas.
IIRC, that is mostly an SEC thing (but they aint messing with out of region games after september, like you said), and the PAC12 is making OOC schedules only happen in the first 3-4 weeks of the season. And from what I've learned about Big10 OOC scheduling by reading up on the OSU game, they get most or all of their OOC games in (except for, again, ND games) early.