How about semi-relevant
Cop out answer: How do you define semi-relevant?
Thought out, elaborated answer: Yes, technically everyone can be semi-relevant, although only for a short period of time (eg Colorado 2016). I do, however, consider that to be a catch lightning in a bottle situation and a constellation that, given the college football reality at that time, only happened like once every decade or so for a program like CU. Given the new reality with NIL and the transfer portal and the consequences these changes bring for a program like CU (eg everyone who proves himself to be somewhat competent can transfer to a "big" program with no strings attached) I would consider the odds of the stars aligning for CU even for only one season to be really low. And that's what it is about at the end of the day, plain probabilities. Few things are ever deterministic, so as far as I am concerned your best bet always is to adapt your behaviour according to the odds.